Bluestein B I, Walczak I M, Chen S Y
Research and Development Group, Ciba-Corning Diagnostics Corporation, Medfield, MA 02052.
Trends Biotechnol. 1990 Jun;8(6):161-8. doi: 10.1016/0167-7799(90)90163-r.
Immunodiagnostic sensors permit sensitive measurement of a wide variety of both high and low molecular mass analytes--serum analytes may be detected at picomolar concentrations. Due to the sensor monitoring antigen--antibody reactions directly, quantitative results are available within seconds to minutes of sample introduction. In recent years, the trend has been for immunodiagnostics to be used at sites away from centralized medical laboratories. Specific requirements associated with such use are being achieved by the development of optical devices incorporating evanescent wave sensors.
免疫诊断传感器能够灵敏地检测各种高分子量和低分子量分析物，血清分析物在皮摩尔浓度下即可被检测到。由于该传感器直接监测抗原 - 抗体反应，在引入样品后的数秒到数分钟内即可获得定量结果。近年来，免疫诊断的趋势是在远离集中式医学实验室的地点使用。通过开发包含倏逝波传感器的光学设备，正在满足与此类使用相关的特定要求。
