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10-羟基-δ2-癸烯酸,一种存在于蜂王浆中的抗生素。

10-Hydroxy-delta 2-decenoic acid, an antibiotic found in royal jelly.

作者信息

BLUM M S, NOVAK A F, TABER S

出版信息

Science. 1959 Aug 21;130(3373):452-3. doi: 10.1126/science.130.3373.452.

Abstract

10-Hydroxy-Delta(2)-decenoic acid, the major component of the lipide fraction of royal jelly, exhibits antibiotic activity against many bacteria and fungi. This fatty acid is less than one-fourth as active as penicillin against Micrococcus pyogenes and less than one-fifth as active as chlortetracycline against Escherichia coli. It also slows the growth rate of Neurospora sitophila and some unidentified molds. The salt of this compound is considerably less active than the free acid.

摘要

10-羟基-Δ(2)-癸烯酸是蜂王浆脂质部分的主要成分,对许多细菌和真菌具有抗菌活性。这种脂肪酸对化脓性微球菌的活性不到青霉素的四分之一,对大肠杆菌的活性不到金霉素的五分之一。它还会减缓嗜热栖热放线菌和一些未鉴定霉菌的生长速度。该化合物的盐类活性比游离酸低得多。

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