Stevens Dennis L.
Infectious Diseases Section, Veterans Affairs Medical Center, 500 West Fort Street (Building 45), Boise, ID 83702, USA.
Curr Infect Dis Rep. 2003 Oct;5(5):379-386. doi: 10.1007/s11908-003-0017-7.
The fulminant nature of group A streptococcal sepsis poses impressive challenges from diagnostic and therapeutic perspectives. Most patients are seen early in the course of infection by primary care providers or emergency department physicians and sent home, only to return in 12 to 24 hours with fully developed group A streptococcal sepsis. Early diagnosis is imperative, but the clinician must have a high index of suspicion. Often, the diagnosis is established only after aggressive interventional management has begun. This review emphasizes salient clinical features and provides general recommendations for critical care management.
A组链球菌败血症的暴发性从诊断和治疗角度带来了巨大挑战。大多数患者在感染早期由初级保健提供者或急诊科医生诊治后被送回家,结果在12至24小时后因A组链球菌败血症完全发作而返回。早期诊断至关重要,但临床医生必须有高度的怀疑指数。通常,只有在开始积极的介入性治疗后才能确诊。本综述强调了显著的临床特征,并为重症监护管理提供了一般建议。