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[瓜德罗普岛(法属西印度群岛)的麻风病:疾病发病率下降,诊断延误增加]

[Leprosy in Guadeloupe (French West Indies): declining disease, increasing diagnosis delay].

作者信息

Muller P, Frédéric M, Salzer B, Strobel M

机构信息

Service des Maladies Infectieuses et Dermatologie, Centre Hospitalier Universitaire, Pointe-à-Pitre, Guadeloupe.

出版信息

Ann Dermatol Venereol. 2003 Jun-Jul;130(6-7):619-21.

Abstract

INTRODUCTION

Endemic for nearly three centuries, leprosy is declining in Guadeloupe: its prevalence has decreased by 75 p. 100 over the last decade. Because it has become rare, it may well be overlooked.

PATIENTS AND METHODS

Retrospective study of all the new cases of leprosy diagnosed in Guadeloupe from May 1996 to May 2001.

RESULTS

In 10 cases of the 41 reported in this study, diagnosis had been delayed by more than 6 months. Nine of these 10 cases presented with classical clinical signs. The mean delay before diagnosis in these 10 cases was of 22 months (range: 7-36 months); the mean number of consultations with a physician before the final diagnosis was of 3.2 (range: 2-8). The mean age at the time of diagnosis in patients in whom diagnosis was delayed was significantly greater than those in whom diagnosis was confirmed rapidly (55 vs. 37 years).

DISCUSSION

In Guadeloupe, one patient out of 4 presenting with leprosy is diagnosed with a delay of more than 6 months, despite a classical clinical presentation. This is deleterious to the patients and health economics. The patients in whom diagnosis was delayed were older. This epidemiological tendency appears inherent to this form of "residual leprosy". The present rareness of the disease is responsible for a lack of knowledge of the disease by the physicians through lack of experience. This phenomenon is also observed for syphilis and measles. There is a real risk of underestimation or erroneous diagnosis.

摘要

引言

麻风病在瓜德罗普岛流行了近三个世纪,目前其发病率正在下降:在过去十年中,发病率已下降了75%。由于它已变得罕见,很可能被忽视。

患者与方法

对1996年5月至2001年5月在瓜德罗普岛诊断出的所有麻风病新病例进行回顾性研究。

结果

在本研究报告的41例病例中,有10例诊断延迟超过6个月。这10例病例中有9例表现出典型的临床症状。这10例病例诊断前的平均延迟时间为22个月(范围:7 - 36个月);最终诊断前平均看医生的次数为3.2次(范围:2 - 8次)。诊断延迟患者的诊断时平均年龄显著高于诊断迅速得到确认的患者(55岁对37岁)。

讨论

在瓜德罗普岛,尽管有典型的临床表现,但每4例麻风病患者中就有1例诊断延迟超过6个月。这对患者和卫生经济学都有害。诊断延迟的患者年龄较大。这种流行病学趋势似乎是这种“残余麻风病”形式所固有的。目前这种疾病的罕见性导致医生由于缺乏经验而对该疾病了解不足。梅毒和麻疹也观察到了这种现象。存在低估或错误诊断的实际风险。

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