Farrow G B, Dewan P A, Taylor R G, Stokes K B, Auldist A W
Department of General Surgery, Royal Children's Hospital, Melbourne, Victoria, Australia.
Pediatr Surg Int. 2003 Sep;19(7):525-8. doi: 10.1007/s00383-002-0766-7. Epub 2003 Sep 11.
A retrospective study was performed of 250 patients with cholelithiasis treated at the Royal Children's Hospital, (RCH) Melbourne, over 25 years by open operation; 32 (12.8%) had proven choledocholithiasis on either preoperative imaging, operative cholangiography (OpCG), or postoperative investigation. A further 3 had underlying congenital biliary abnormalities and were excluded from further study. Thirty-one of the 32 were explored at open operation, 27 after OpCG and 4 on clinical grounds. One retained common-bile-duct (CBD) stone was undetected until the postoperative period (1/250, 0.25%). Seven ducts were not cleared, giving a duct exploration failure rate of 22.6% (7/31). All 8 retained CBD stones were identified in the early postoperative period and managed with a variety of techniques, including endoscopic retrograde cholangio-pancreatography (ERCP). The incidence of retained stones after open CBD exploration was high (22.6%), and can be attributed to difficulties in operative technique dealing with the smaller paediatric CBD. In addition, haemolytic disease seems to induce a propensity for choledocholithiasis. Given the small numbers presenting with cholelithiasis to RCH (10 per year), it is suggested that a selective approach to CBD exploration is appropriate in children. With the increasing use of laparoscopic cholecystectomy in children and the inherent technical difficulties of laparoscopic operative cholangiography, ERCP may offer an alternative solution in dealing with CBD stones rather than open or laparoscopic CBD exploration.
对墨尔本皇家儿童医院(RCH)25年来接受开放手术治疗的250例胆石症患儿进行了一项回顾性研究;32例(12.8%)在术前影像学检查、术中胆管造影(OpCG)或术后检查中证实存在胆总管结石。另外3例有潜在的先天性胆道异常,被排除在进一步研究之外。32例中的31例接受了开放手术探查,27例在OpCG后探查,4例基于临床原因探查。1例残留胆总管(CBD)结石直到术后才被发现(250例中的1例,0.25%)。7条胆管未清理干净,胆管探查失败率为22.6%(7/31)。所有8例残留的CBD结石均在术后早期被发现,并采用了包括内镜逆行胰胆管造影(ERCP)在内的多种技术进行处理。开放CBD探查后残留结石的发生率很高(22.6%),这可能归因于处理小儿较小的CBD时手术技术存在困难。此外,溶血性疾病似乎易引发胆总管结石。鉴于RCH胆石症患儿数量较少(每年10例),建议对儿童采用选择性CBD探查方法。随着腹腔镜胆囊切除术在儿童中的应用增加以及腹腔镜术中胆管造影存在固有的技术困难,ERCP可能为处理CBD结石提供一种替代方案,而非开放或腹腔镜CBD探查。