Blanckaert H, Frans J, Bosteels J, Hanssens M, Verhaegen J
Laboratory of Microbiology, Centraal Dienstengebouw 7th floor, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium.
Eur J Clin Microbiol Infect Dis. 2003 Oct;22(10):619-21. doi: 10.1007/s10096-003-1002-7. Epub 2003 Sep 12.
The purpose of the study presented here was to confirm the high yield of group B streptococci (GBS) on Granada medium for the detection of pregnant GBS carriers and to compare the results with those obtained using standard Columbia blood agar at two participating centers in Belgium. Culture results of the vaginorectal swabs obtained at the two centers were also compared. A total of 1,142 samples (838 in Leuven and 304 in Bonheiden) obtained from consecutive pregnant women were cultured onto both media. Of all GBS carriers 84.7% were detected on Columbia blood agar and 93.4% on Granada agar ( P<0.01, McNemar test). The addition of Granada agar was responsible for a 15% higher rate of detection of GBS carriers. As a result of this study, both participating hospitals will use a combination of Granada agar with Columbia blood agar for optimal GBS screening in the future.
本文所呈现的研究目的是确认在格拉纳达培养基上检测妊娠B族链球菌（GBS）携带者时GBS的高检出率，并将结果与比利时两个参与中心使用标准哥伦比亚血琼脂获得的结果进行比较。还比较了在两个中心采集的阴道直肠拭子的培养结果。从连续的孕妇中采集了总共1142份样本（鲁汶838份，博赫丹304份），并在两种培养基上进行培养。在所有GBS携带者中，哥伦比亚血琼脂的检出率为84.7%，格拉纳达琼脂的检出率为93.4%（McNemar检验，P<0.01）。添加格拉纳达琼脂使GBS携带者的检出率提高了15%。作为本研究的结果，未来两个参与医院都将使用格拉纳达琼脂与哥伦比亚血琼脂的组合进行最佳的GBS筛查。
