Noda N, Kogetsu H, Kawasaki T, Miyahara K
Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, Japan.
Phytochemistry. 1992 Aug;31(8):2761-6. doi: 10.1016/0031-9422(92)83626-a.
Two minor ether-soluble resin glycosides, scammonins VII and VIII, were isolated from Radix Scammoniae, the roots of Convolvulus scammonia. In addition to (2S)-2-methylbutyric acid and tiglic acid, they are composed, respectively, of orizabic acid A and a new glycosidic acid named scammonic acid B, with similar macrocyclic ester structures to those of the scammonic acid A-based scammonins I-VI. Isolation of genuine scammonins III-V, which were previously obtained as peracetates, is also described.
从旋花科植物药旋花（Convolvulus scammonia）的根中分离出两种次要的醚溶性树脂糖苷，即司卡摩宁VII和VIII。除了（2S）-2-甲基丁酸和惕各酸外，它们分别由奥里扎酸A和一种名为司卡摩酸B的新糖苷酸组成，其大环酯结构与基于司卡摩酸A的司卡摩宁I-VI相似。本文还描述了之前以过乙酸酯形式获得的纯司卡摩宁III-V的分离方法。
