通过DNA流式细胞术测定非肿瘤性及良性黑素细胞和乳腺病变中的非整倍体。
Aneuploidy in nonneoplastic and benign melanocytic and breast lesions determined by DNA flow cytometry.
作者信息
Frei J V, Martinez V J
机构信息
Department of Pathology, University of Western Ontario, London, Canada.
出版信息
Mod Pathol. 1992 Nov;5(6):600-2.
PMID:1369792
Abstract
A total of ten of 60 nonneoplastic lesions and eight of 76 benign neoplasms of skin and breast showed an aneuploid peak in DNA flow cytometry profiles obtained from archival paraffin blocks. This confirms previous similar scattered reports and emphasizes that caution needs to be exercised in interpreting aneuploidy in DNA flow cytometry to mean preneoplasia, neoplasia, or malignancy.
摘要
在从存档石蜡块获取的DNA流式细胞术图谱中，60例非肿瘤性皮肤病变中有10例，76例皮肤和乳腺良性肿瘤中有8例显示非整倍体峰。这证实了先前类似的零散报道，并强调在将DNA流式细胞术中的非整倍体解释为瘤前病变、肿瘤或恶性肿瘤时需要谨慎。
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