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[L4-L5椎体椎间盘随年龄发生的矿物质变化]

[Mineral changes occurring with age in the intervertebral disks of L4-L5 vertebrae].

作者信息

Niedźwiedzki T, Pawlikowski M, Brudnicki J

机构信息

III Kliniki Chirurgii AM w Krakowie.

出版信息

Chir Narzadow Ruchu Ortop Pol. 1992;57(1-3):225-9.

PMID:1369965
Abstract

The results of mineralogical examination of 26 L4-L5 intervertebral discs taken from cadavers has been presented. Radiology did not reveal marked osteoarthritic changes at this level. The age of the individuals at the fatal accident ranged from 4 to 87 years (mean 41.2). -- Scanning microscopy, atom absorbtion spectroscopy and roentgen microscopy was used in the examination. Two age related phenomena were discovered; demineralisation of the nucleus pulposus and mineralisation of the anulus fibrosus. Two types of mineralisation were found; the microscopic one visible as granules of different shape and size consisting of crystalline hydroxyapatite aggregates and the one detectable exclusively by sensitive chemical methods as an increase of Ca and P content and disturbance of the remaining elements content in biological structures.

摘要

本文展示了对取自尸体的26个L4-L5椎间盘进行矿物学检查的结果。放射学检查未发现该水平有明显的骨关节炎变化。致命事故中个体的年龄范围为4至87岁(平均41.2岁)。——检查中使用了扫描显微镜、原子吸收光谱法和X射线显微镜。发现了两种与年龄相关的现象;髓核脱矿和纤维环矿化。发现了两种矿化类型;微观矿化表现为不同形状和大小的颗粒,由结晶羟基磷灰石聚集体组成,另一种仅通过灵敏的化学方法检测到,表现为生物结构中钙和磷含量增加以及其他元素含量紊乱。

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