用氚水处理果蝇幼虫后，果蝇中生殖细胞和体细胞突变的诱导。

Germinal and somatic mutation induction in Drosophila after treatment of larvae with tritiated water.

作者信息

Ribas G, Torres C, Batiste-Alentorn M, Xamena N, Creus A, Marcos R

机构信息

Departament de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Spain.

出版信息

Mutat Res. 1992 Jan;278(1):43-6. doi: 10.1016/0165-1218(92)90284-7.

DOI:10.1016/0165-1218(92)90284-7

PMID:1370118

Abstract

The present study was carried out to evaluate the mutagenicity of tritium, administered as tritiated water, in Drosophila melanogaster. Larvae were fed on tritium-treated medium during their development. Germinal and somatic mutation induction was detected by means of the sex-linked recessive lethal and the wing spot tests, respectively. Our results show that beta-radiation from tritium is able to induce significant increases in the frequency of both germinal and somatic mutations.

摘要

本研究旨在评估以氚水形式给予的氚对黑腹果蝇的致突变性。幼虫在发育过程中取食经氚处理的培养基。分别通过性连锁隐性致死试验和翅斑试验检测生殖细胞和体细胞突变的诱导情况。我们的结果表明，氚的β辐射能够显著提高生殖细胞和体细胞突变的频率。