Prostate-specific antigen and prostate-specific acid phosphatase in neuroendocrine cells of prostate cancer.
作者信息
Cohen R J, Glezerson G, Haffejee Z
机构信息
Department of Anatomical Pathology, School of Pathology, South African Institute for Medical Research, Johannesburg.
出版信息
Arch Pathol Lab Med. 1992 Jan;116(1):65-6.
PMID:1370878
Abstract
Prostate-specific antigen is a specific immunohistochemical marker of benign prostatic epithelium and prostate cancer. A subpopulation of neuroendocrine cells seen in 50% of cancers do not produce this protein marker. These cells appear to secrete prostate-specific acid phosphatase. This finding may explain the marked variation in serum prostate-specific antigen levels in all stages of prostate cancer.
摘要
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