前列腺标志物的临床应用。I. 利用免疫组织化学技术对前列腺肿瘤进行分类。
Clinical application of prostatic markers. I. Classification of prostatic tumours using immunohistochemical techniques.
作者信息
Svanholm H, Hørder M
机构信息
Department of Pathology, Odense University Hospital, Denmark.
出版信息
Scand J Urol Nephrol Suppl. 1988;107:65-70.
PMID:2453920
Abstract
Immunohistochemical techniques using antibodies to prostate specific antigen (PSA) and prostate specific acid phosphatase (PAP) have greatly increased the feasibility of reliable diagnosis of primary or metastatic prostatic carcinoma. A review of the literature showed the diagnostic specificity of antibodies to PSA or PAP to be 100% and 87-100%, respectively. The corresponding figures for diagnostic sensitivity were 94-100% and 90-100%.
摘要
使用针对前列腺特异性抗原（PSA）和前列腺特异性酸性磷酸酶（PAP）的抗体的免疫组织化学技术，极大地提高了可靠诊断原发性或转移性前列腺癌的可行性。文献综述显示，针对PSA或PAP的抗体的诊断特异性分别为100%和87 - 100%。相应的诊断敏感性数字分别为94 - 100%和90 - 100%。
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