绒泡菌玻连蛋白样蛋白：一种具有独特氨基末端序列的依赖精氨酸-甘氨酸-天冬氨酸的细胞铺展蛋白。
Physarum vitronectin-like protein: an Arg-Gly-Asp-dependent cell-spreading protein with a distinct NH2-terminal sequence.
作者信息
Miyazaki K, Hamano T, Hayashi M
机构信息
Department of Biology, Ochanomizu University, Tokyo, Japan.
出版信息
Exp Cell Res. 1992 Mar;199(1):106-10. doi: 10.1016/0014-4827(92)90467-m.
PMID:1370938
Abstract
A 70-kDa protein cross-reacted with anti-bovine vitronectin was isolated from slime mold Physarum polycephalum. The NH2-terminal amino acid sequence of the protein, referred to as Physarum vitronectin-like protein, did not share any homology with those of animal vitronectins. It had cell-spreading activity, which was specifically inhibited by an Arg-Gly-Asp (RGD)-containing peptide.
摘要
从多头绒泡菌中分离出一种与抗牛玻连蛋白发生交叉反应的70 kDa蛋白质。该蛋白质的氨基末端氨基酸序列，被称为绒泡菌玻连蛋白样蛋白，与动物玻连蛋白的序列没有任何同源性。它具有细胞铺展活性，这种活性被一种含精氨酸-甘氨酸-天冬氨酸（RGD）的肽特异性抑制。
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