Goto K, Wakayama K, Sonoda H, Ogawa T
Department of Pediatrics, Medical College of Oita, Japan.
Electroencephalogr Clin Neurophysiol. 1992 Mar;82(3):197-202. doi: 10.1016/0013-4694(92)90167-g.
This study was conducted to quantify sequential changes in electroencephalogram (EEG) continuity for 24 h in very premature infants. For a total of 122 days, continuous 2-channel EEG recording was conducted for 28 premature infants from 26 to 33 weeks of conceptional age (CA). None of the infants showed evidence of neurological impairment during hospitalization. Normal neurological outcome was noted at a minimum 12 months of age. By classifying each 5.5 min epoch according to EEG continuity, the number of contiguous epochs of each series of discontinuous type (DTs) and the number of epochs between two series of discontinuous type (IDTIs) were counted at each CA. The duration of DT decreased with increasing CA. The mean duration remained at 13-16 min after 29 weeks CA. The mean duration of each IDTI increased with CA, up to about 1 h at 33 weeks. A constant period of DTs was noted at longer intervals with increasing CA. These changes appear related to the development of sleep state organization with CA.
本研究旨在量化极早产儿24小时脑电图（EEG）连续性的连续变化。在总共122天的时间里，对28名孕龄（CA）为26至33周的早产儿进行了连续两通道EEG记录。所有婴儿在住院期间均未表现出神经功能损害的迹象。在至少12个月大时记录到正常的神经学结局。根据EEG连续性对每个5.5分钟时段进行分类，计算每个不连续类型系列（DTs）的连续时段数以及两个不连续类型系列之间的时段数（IDTIs）。DT的持续时间随CA增加而减少。CA达到29周后，平均持续时间保持在13 - 16分钟。每个IDTI的平均持续时间随CA增加，在33周时达到约1小时。随着CA增加，DTs的恒定周期出现的间隔时间变长。这些变化似乎与睡眠状态组织随CA的发育有关。
