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The effects of a Senecio alkaloid (monocrotaline) on human embryo liver in tissue culture.

作者信息

HIRCHINSON V, HILL K R

出版信息

Br J Cancer. 1960 Dec;14(4):637-46. doi: 10.1038/bjc.1960.70.

DOI:10.1038/bjc.1960.70
PMID:13714530
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2074201/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1813/2074201/5933ee603d4c/brjcancer00365-0061-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1813/2074201/d7e63645513c/brjcancer00365-0064-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1813/2074201/d53a1aaaf4cc/brjcancer00365-0063-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1813/2074201/5044f9d59c18/brjcancer00365-0062-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1813/2074201/5933ee603d4c/brjcancer00365-0061-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1813/2074201/d7e63645513c/brjcancer00365-0064-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1813/2074201/d53a1aaaf4cc/brjcancer00365-0063-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1813/2074201/5044f9d59c18/brjcancer00365-0062-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1813/2074201/5933ee603d4c/brjcancer00365-0061-a.jpg

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1
The effects of a Senecio alkaloid (monocrotaline) on human embryo liver in tissue culture.千里光生物碱（野百合碱）对组织培养中的人胚肝的影响。
Br J Cancer. 1960 Dec;14(4):637-46. doi: 10.1038/bjc.1960.70.
2
Variation of liver function in immature fowls and susceptibility to seneciphylline.幼禽肝功能的变化及对seneciphylline的易感性。
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Further observations on the subacute and chronic liver changes in rats after a single dose of various pyrrolizidine (Senecio) alkaloids.关于大鼠单次给予各种吡咯里西啶（千里光）生物碱后亚急性和慢性肝脏变化的进一步观察
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Effect of dietary Senecio jacobaea and injected Senecio alkaloids and monocrotaline on guinea pigs.
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(STUDIES ON PYRROLIZIDINE ALKALOIDS. II. THE ALKALOIDS OF SENECIO CRUENTUS D. C.).（吡咯里西啶生物碱的研究。II. 瓜叶千里光的生物碱）
Yao Xue Xue Bao. 1964 Mar;11:168-73.
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[Studies on the alkaloids of Senecio scandens growing in Guangdong].[对生长于广东的千里光生物碱的研究]
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Characterization of hepatic DNA damage induced in rats by the pyrrolizidine alkaloid monocrotaline.由吡咯里西啶生物碱野百合碱诱导的大鼠肝脏DNA损伤的特征
Cancer Res. 1984 Apr;44(4):1505-9.
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[On the problem of the effect of platyphylline on morphological structures of the organism in experimental animals].
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Nature. 1962 Aug 11;195:570-3. doi: 10.1038/195570a0.

引用本文的文献

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Hepatic veno-occlusive disease as a result of a traditional remedy: confirmation of toxic pyrrolizidine alkaloids as the cause, using an in vitro technique.一种传统疗法导致的肝静脉闭塞病：运用体外技术确证有毒吡咯里西啶生物碱为病因
J Clin Pathol. 2002 Sep;55(9):676-9. doi: 10.1136/jcp.55.9.676.

本文引用的文献

1
Primary liver tumours in rats following feeding with alkaloids of Senecio jacobaea.用千里光生物碱喂养大鼠后出现的原发性肝肿瘤。
Br J Cancer. 1950 Dec;4(4):405-10. doi: 10.1038/bjc.1950.39.
2
Pathological changes in rats as a result of treatment with monocrotaline.用野百合碱治疗后大鼠的病理变化。
Br J Cancer. 1955 Mar;9(1):229-37. doi: 10.1038/bjc.1955.19.
3
Some observations on liver disease in the West Indies.关于西印度群岛肝脏疾病的一些观察
Trans R Soc Trop Med Hyg. 1959 May;53(3):217-30; discussion 231-7. doi: 10.1016/0035-9203(59)90002-1.
4
Origin of binucleate cells in connective tissue cultures, with a contribution to the problem of amitosis.结缔组织培养中双核细胞的起源，兼对无丝分裂问题的探讨。
Z Mikrosk Anat Forsch. 1958;64(2):174-91.
5
Irradiation of cells in tissue culture. I. Giant cell induction in strain cultures versus elements from primary explants.组织培养中细胞的辐照。I. 菌株培养物中巨细胞的诱导与原代外植体成分的比较
Z Zellforsch Mikrosk Anat. 1957;47(2):158-74.
6
Human cell culture: morphology of the Detroit strains.人类细胞培养：底特律菌株的形态学
Cancer Res. 1957 Aug;17(7):668-76.
7
Transformation of normal cells in tissue culture: its significance relative to malignancy and virus vaccine production.组织培养中正常细胞的转化：其与恶性肿瘤及病毒疫苗生产的相关性
Br J Exp Pathol. 1957 Apr;38(2):138-54.
8
Plants as aetiological factor in veno-occlusive disease of the liver.
Lancet. 1957 May 11;272(6976):960-2. doi: 10.1016/s0140-6736(57)91283-7.
9
Human nasal cells in continuous culture. I. Establishment of two lines of epithelial-like cells.
Proc Soc Exp Biol Med. 1956 Aug-Sep;92(4):867-71. doi: 10.3181/00379727-92-22638.
10
Neoplastic changes developing in epithelial cell lines derived from normal persons.源自正常人的上皮细胞系中发生的肿瘤性变化。
Science. 1956 Jul 20;124(3212):127-9. doi: 10.1126/science.124.3212.127-a.