Domagala W, Bedner E, Chosia M, Weber K, Osborn M
Department of Tumor Pathology, Medical Academy, Szczecin, Poland.
Acta Cytol. 1992 Mar-Apr;36(2):241-5.
Fine needle aspirates and touch imprints of 36 hyperplastic (reactive) lymph nodes were tested for the presence of keratin and desmin. Keratin-positive cells with morphologic characteristics corresponding to extrafollicular (fibroblastic) reticulum cells were found in 18% of the fine needle aspirates and 42% of the touch imprints. The number of keratin-positive reticulum cells varied from 1 to greater than 30 per slide. Desmin-positive cells with similar morphology were found in 23% of fine needle aspirates and 37% of touch imprints, and the number of such cells per slide ranged from 2 to greater than 70. The relatively frequent occurrence of keratin-positive reticulum cells in these preparations from hyperplastic lymph nodes should be taken into account if keratin antibodies are used to search for carcinoma micrometastases.
对36个增生性（反应性）淋巴结的细针穿刺抽吸物和触摸印片进行了角蛋白和结蛋白检测。在18%的细针穿刺抽吸物和42%的触摸印片中发现了具有对应于滤泡外（成纤维细胞）网状细胞形态特征的角蛋白阳性细胞。每张载玻片上角蛋白阳性网状细胞的数量从1个到超过30个不等。在23%的细针穿刺抽吸物和37%的触摸印片中发现了形态相似的结蛋白阳性细胞，每张载玻片上此类细胞的数量从2个到超过70个不等。如果使用角蛋白抗体来寻找癌微转移灶，那么在这些增生性淋巴结的标本中角蛋白阳性网状细胞相对频繁出现的情况应予以考虑。
