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耳部流脓的最佳处理方法。

Optimum management of the discharging ear.

作者信息

Ruddy J, Bickerton R C

机构信息

ENT Department, Queen Elizabeth Hospital, Edgbaston, Birmingham, England.

出版信息

Drugs. 1992 Feb;43(2):219-35. doi: 10.2165/00003495-199243020-00008.

Abstract

Discharge from the ear can be the result of many disease processes. The ear may discharge blood, pus, cerebrospinal fluid (CSF) or wax. Keratosis obturans, stenosis of the external meatus and benign tumours of the external meatus all lead to wax build-up, which may cause recurrent attacks of otitis externa. Malignant tumours, such as basal cell carcinoma, squamous cell carcinoma and tumours of ceruminous gland origin may also present with discharge. Tumours should be excluded by submitting all material removed from the external canal for histological examination. Single or multiple abscesses (known as furuncles) may occur in the hair follicles in the skin of the external acoustic meatus (EAM). Compulsive scratching, hearing aids and foreign bodies placed in the ear predispose to otitis externa, which is also often associated with infection by Pseudomonas aeruginosa, Staphylococcus aureus and faecal organisms. Management may be with aluminium acetate 14%, topical antibiotic/steroid drops, a gauze wick soaked with icthammol 10% in glycerin or polymyxin B sulphate--neomycin sulphate--hydrocortisone acetate cream placed into the EAM and replaced every 24 to 48 hours, or systemic antibiotics according to severity. Malignant (necrotising) otitis externa causes progressive destruction of the temporal bone, and cranial nerve palsies (usually facial first). Treatment is limited debridement of infected bone, accompanied by intravenous aminoglycosides, and local antibiotic treatment and aural cleanout or oral ciprofloxacin. Middle ear conditions causing discharge include acute otitis media, infected grommets, traumatic perforations and chronic suppurative otitis media, as well as tumours of the ear canal skin and middle ear, radiation-induced otitis externa and osteoradionecrosis of the temporal bone, tuberculosis, Langerhans cell histiocytosis, spontaneous or post-traumatic CSF leaks, Wegeners granulomatosis and immune deficiency states. Topical application of aminoglycoside antibiotics to the middle ear of laboratory animals such as rats, guinea pigs and chinchillas causes sensorineural hearing loss, an effect rarely seen clinically in humans. If the external acoustic meatus and tympanic membrane are obscured by discharge cotton buds, microsuction equipment or syringing are used to remove it. It is often useful to initiate treatment (usually with topical drops, wicks or an oral antibiotic) with a provisional diagnosis. A full examination and adequate visualisation of the tympanic membrane must eventually be performed, if necessary under anaesthesia, or else serious progressive conditions may be neglected. The most useful initial investigation is a swab sent for bacteriological assessment; other investigations are usually indicated by clinical findings and the provisional diagnosis.

摘要

耳部流出物可能是多种疾病过程的结果。耳部可能流出血液、脓液、脑脊液(CSF)或耵聍。外耳道闭锁、外耳道狭窄和外耳道良性肿瘤都会导致耵聍积聚,这可能会引起外耳道炎反复发作。恶性肿瘤,如基底细胞癌、鳞状细胞癌和耵聍腺来源的肿瘤也可能表现为耳部流出物。应将从外耳道取出的所有组织送检进行组织学检查以排除肿瘤。外耳道皮肤的毛囊中可能出现单个或多个脓肿(称为疖肿)。强迫性搔抓、助听器和耳部异物会诱发外耳道炎,外耳道炎也常与铜绿假单胞菌、金黄色葡萄球菌和肠道菌感染有关。治疗可使用14%的醋酸铝、局部用抗生素/类固醇滴剂、用10%鱼石脂甘油浸泡的纱布条或硫酸多粘菌素B - 硫酸新霉素 - 醋酸氢化可的松乳膏放入外耳道,每24至48小时更换一次,或根据病情严重程度使用全身性抗生素。恶性(坏死性)外耳道炎会导致颞骨进行性破坏,并出现脑神经麻痹(通常首先是面神经)。治疗方法是对感染的骨质进行有限的清创,同时静脉注射氨基糖苷类药物,并进行局部抗生素治疗和耳部清理,或口服环丙沙星。导致耳部流出物的中耳疾病包括急性中耳炎、感染的鼓膜通气管、外伤性穿孔和慢性化脓性中耳炎,以及耳道皮肤和中耳的肿瘤、放射性外耳道炎和颞骨放射性骨坏死、结核病、朗格汉斯细胞组织细胞增多症、自发性或创伤后脑脊液漏、韦格纳肉芽肿和免疫缺陷状态。在大鼠、豚鼠和龙猫等实验动物的中耳局部应用氨基糖苷类抗生素会导致感音神经性听力损失,这种情况在人类临床中很少见。如果外耳道和鼓膜被流出物遮挡,可用棉签、微吸设备或冲洗来清除。根据初步诊断开始治疗(通常使用局部滴剂、纱条或口服抗生素)往往很有用。最终必须进行全面检查并充分观察鼓膜,必要时在麻醉下进行,否则可能会忽略严重的进行性疾病。最有用的初步检查是送检拭子进行细菌学评估;其他检查通常根据临床发现和初步诊断来进行。

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