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编码小鼠谷氨酸受体通道家族新成员的cDNA的分子克隆

Molecular cloning of a cDNA encoding a novel member of the mouse glutamate receptor channel family.

作者信息

Yamazaki M, Araki K, Shibata A, Mishina M

机构信息

Department of Neuropharmacology, Niigata University, Japan.

出版信息

Biochem Biophys Res Commun. 1992 Mar 16;183(2):886-92. doi: 10.1016/0006-291x(92)90566-4.

DOI:10.1016/0006-291x(92)90566-4
PMID:1372507
Abstract

The primary structure of a novel putative subunit of the mouse glutamate receptor channel, designated as delta 1, has been deduced by cloning and sequencing the cDNA. The delta 1 subunit shows 21-25% amino acid sequence identity with previously characterized rodent glutamate receptor channel subunits and thus may represent a new subfamily of the glutamate receptor channel.

摘要

通过对cDNA进行克隆和测序,已推导得到一种新的假定小鼠谷氨酸受体通道亚基(命名为δ1)的一级结构。δ1亚基与先前鉴定的啮齿动物谷氨酸受体通道亚基具有21%-25%的氨基酸序列同一性,因此可能代表谷氨酸受体通道的一个新亚家族。

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Molecular cloning of a cDNA encoding a novel member of the mouse glutamate receptor channel family.编码小鼠谷氨酸受体通道家族新成员的cDNA的分子克隆
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