Dieckmann K P, Bornhoeft G, Gross A J
Urologische Klinik und Institut für Pathologie, Klinikum Steglitz, FU Berlin.
Urologe A. 1992 Jan;31(1):52-4.
A 25-year-old patient with testicular teratoma (pathological stage I) relapsed with a solitary, symptomatic metastasis in the right humerus 8 months after unilateral orchiectomy and lymphadenectomy. Treatment consisted in three cycles of standard chemotherapy with etoposide, bleomycin and cisplatin (the last replaced by carboplatin in courses 2 and 3). No supplementary treatment proved necessary to achieve complete remission and complete physical rehabilitation. Only four cases of solitary bone metastasis of testicular germ cell tumors have been reported previously. The present case illustrates that, contrary to previous reports, symptomatic skeletal metastases of germ cell tumors can safely be treated with standard chemotherapy alone.
一名25岁睾丸畸胎瘤患者(病理分期I期),在单侧睾丸切除及淋巴结清扫术后8个月,出现右肱骨孤立性、有症状的转移灶。治疗方案为采用依托泊苷、博来霉素和顺铂进行三个周期的标准化疗(在第2和第3疗程中顺铂被卡铂替代)。无需额外治疗即可实现完全缓解和完全身体康复。此前仅报道过4例睾丸生殖细胞肿瘤的孤立性骨转移病例。本病例表明,与之前的报道相反,生殖细胞肿瘤有症状的骨转移仅用标准化疗即可安全治疗。