Babaya K, Tsumatani K, Natsume O, Yoshie T, Kubota K, Ozono S, Hirao Y, Okajima E
Gan To Kagaku Ryoho. 1986 Mar;13(3 Pt 1):604-7.
A 38-year-old man was admitted to Nara Medical University Hospital on Feb.7,1983, because of swelling of the scrotal contents on the right side and elevated serum AFP, beta-HCG and LDH suggestive of testicular tumor. Right orchiectomy was carried out and a pathological diagnosis of embryonal cell carcinoma of the right testis (pT3N0M1) was made. The patient, upon evidence of multiple pulmonary metastases, was treated with a combination chemotherapy of cis-Diamminedichloroplatinum, vincristine and peplomycin. After three courses of combination chemotherapy, pulmonary metastases were decreased, but their foci persisted. The patient was then treated with Etoposide 62 mg/m2 daily for 5 days every three weeks, and after this course, complete remission of pulmonary metastases was obtained. The patient recieved 3 courses of Etoposide and retroperitoneal lymph node dissection, and has since shown no evidence of disease for 2 years and 4 months after surgery.
一名38岁男性于1983年2月7日因右侧阴囊内容物肿胀以及血清甲胎蛋白、β-人绒毛膜促性腺激素和乳酸脱氢酶升高（提示睾丸肿瘤）入住奈良医科大学医院。实施了右侧睾丸切除术，病理诊断为右侧睾丸胚胎性细胞癌（pT3N0M1）。该患者在发现多处肺转移后，接受了顺铂、长春新碱和培普利霉素联合化疗。三个疗程的联合化疗后，肺转移灶减少，但仍有病灶残留。随后患者接受依托泊苷治疗，剂量为62mg/m²，每三周每日给药5天，此疗程后肺转移灶完全缓解。该患者接受了3个疗程的依托泊苷治疗及腹膜后淋巴结清扫术，术后2年4个月以来未出现疾病迹象。
