Mazzini L, Galante M, Rezzonico M, Kokodoko A
Clinica del Lavoro Foundation Medical Center of Rehabilitation, Institute of Care and Research, Veruno, Italy.
Schweiz Arch Neurol Psychiatr (1985). 1992;143(1):75-80.
This work focuses on the neurophysiological features in a patient with action myoclonus and mental deterioration following methylbromide intoxication. The patient is a 28-year-old man, without respiratory distress or exposure to other toxics. Myoclonus improved with polytherapy (clonazepam, 5-HT, carbidopa, GABA). The neurophysiological and neuropsychological evidence in this patient suggests a possible double site of action of methylbromide at cortical and subcortical levels.
这项工作聚焦于一名在甲基溴中毒后出现动作性肌阵挛和精神衰退患者的神经生理学特征。该患者为一名28岁男性,无呼吸窘迫且未接触其他毒物。联合治疗(氯硝西泮、5-羟色胺、卡比多巴、γ-氨基丁酸)使肌阵挛症状得到改善。该患者的神经生理学和神经心理学证据表明甲基溴可能在皮层和皮层下水平存在双重作用位点。