Speleman F, Van Roy N, Wiegant J, Dierick A M, Uyttendaele D, Leroy J G
Department of Medical Genetics, University Hospital, Ghent, Belgium.
Genes Chromosomes Cancer. 1992 Mar;4(2):188-91. doi: 10.1002/gcc.2870040214.
Fluorescence in situ hybridization (FISH) using chromosome-specific plasmid libraries and chromosome region-specific DNA markers allowed the characterization of a t(10;22;11) (p11.2;q12;q24) in a Ewing's sarcoma (ES). This study illustrates the usefulness of molecular cytogenetic analysis of ES, especially for determining the localization of the translocated 11q24-25 segment in complex or variant translocations.