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[阴茎癌及其治疗]

[Cancer of the penis and its treatment].

作者信息

Kamidono S

机构信息

Department of Urology, Kobe University School of Medicine.

出版信息

Nihon Hinyokika Gakkai Zasshi. 1992 Jan;83(1):1-15. doi: 10.5980/jpnjurol1989.83.1.

Abstract

It had been believed that carcinoma of the penis was rather rare in the developed countries comparing with that in the under-developing countries, however, the recent epidemiological studies failed to reveal any clear difference of the incidence of carcinoma of the penis all over the world. In these days so called successful treatment is coming to be evaluated by the quality of life (QOL) after surgical or nonsurgical treatment (especially sexual function tended to be considered very important factors altering QOL). I want to emphasize the following issues in this report. 1. Erythroplasia of Queyrat and Bowen's disease are carcinoma in situ and should be dealt as carcinoma of the penis. 2. relation of human papilloma virus and carcinoma of penis. 3. usefulness of TNM classification over Jackson's classification. 4. SCC antigen is a reliable tumor marker of carcinoma of the penis? 5. effectiveness of chemotherapy based on BLM combined with radiation therapy for carcinoma of the penis. 6. usefulness of Mohs microscopically controlled surgery and modified groin dissection. It is generally accepted that since carcinoma of the penis is a rare disease and for one institution up to 50 cases can be experienced during 20 years in Japan, there exist no integrated study involving a large number of institutions. I really wish a certain form of group study to be completed and the results from this study utilized to overcome the present problems for the treatment of carcinoma of the penis.

摘要

过去人们一直认为,与发展中国家相比,阴茎癌在发达国家较为罕见。然而,最近的流行病学研究并未揭示全球范围内阴茎癌发病率的任何明显差异。如今,所谓的成功治疗正开始通过手术或非手术治疗后的生活质量(QOL)来评估(特别是性功能往往被视为改变生活质量的非常重要的因素)。在本报告中,我想强调以下几个问题。1. 凯腊增殖性红斑和鲍恩病是原位癌,应按阴茎癌处理。2. 人乳头瘤病毒与阴茎癌的关系。3. TNM分类相对于杰克逊分类的实用性。4. SCC抗原是阴茎癌可靠的肿瘤标志物吗?5. 基于博来霉素联合放疗的化疗对阴茎癌的有效性。6. 莫氏显微控制手术和改良腹股沟淋巴结清扫术的实用性。一般认为,由于阴茎癌是一种罕见疾病,在日本一个机构20年内最多能遇到50例,因此不存在涉及大量机构的综合研究。我真希望能完成某种形式的小组研究,并利用该研究结果来克服目前阴茎癌治疗中的问题。

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