Edsmyr F, Andersson L, Esposti P L
Cancer. 1985 Sep 15;56(6):1257-63. doi: 10.1002/1097-0142(19850915)56:6<1257::aid-cncr2820560606>3.0.co;2-a.
Cancer of the penis is an uncommon disease in the western part of the world but it represents a significant portion of male cancer in other countries as in Asia, Africa, and South America, where in certain areas it accounts for 20% of the cancer occurrence in male patients. The treatment has been based mainly on surgical excision with or without regional lymphadenectomy. Chemotherapy with bleomycin has had some effectiveness in advanced disease. A mode of combination therapy with bleomycin and irradiation has been evaluated in patients with carcinoma of the penis. The results compare favorably with surgical treatment with respect to cure of the disease and patient survival, and it has the advantage of preserving sexual function in most of the cases. This combined therapy is useful even in patients with relatively extensive local tumor.
阴茎癌在世界西部是一种罕见疾病，但在亚洲、非洲和南美洲等其他国家，它在男性癌症中占很大比例，在某些地区，它占男性患者癌症发生率的20%。治疗主要基于手术切除，可伴有或不伴有区域淋巴结清扫术。博来霉素化疗对晚期疾病有一定疗效。已对阴茎癌患者评估了博来霉素与放疗的联合治疗模式。在疾病治愈和患者生存方面，该结果与手术治疗相比具有优势，并且在大多数情况下具有保留性功能的优点。这种联合治疗即使对局部肿瘤相对广泛的患者也有用。
