New polyenic antibiotics active against gram-positive and gram-negative bacteria. VI. Non-lactonic polyene antibiotic, enacyloxin IIa, inhibits binding of aminoacyl-tRNA to A site of ribosomes.
作者信息
Watanabe T, Okubo N, Suzuki T, Izaki K
机构信息
Department of Agricultural Chemistry, Faculty of Agriculture, Tohoku University, Sendai, Japan.
出版信息
J Antibiot (Tokyo). 1992 Apr;45(4):572-4. doi: 10.7164/antibiotics.45.572.
PMID:1375592
Abstract
摘要
相似文献
1
New polyenic antibiotics active against gram-positive and gram-negative bacteria. VI. Non-lactonic polyene antibiotic, enacyloxin IIa, inhibits binding of aminoacyl-tRNA to A site of ribosomes.对革兰氏阳性菌和革兰氏阴性菌有效的新型多烯抗生素。VI. 非内酯型多烯抗生素恩西洛辛IIa抑制氨酰tRNA与核糖体A位点的结合。
J Antibiot (Tokyo). 1992 Apr;45(4):572-4. doi: 10.7164/antibiotics.45.572.
2
New polyenic antibiotics active against gram-positive and gram-negative bacteria. IV. Structural elucidation of enacyloxin IIa.
J Antibiot (Tokyo). 1992 Apr;45(4):470-5. doi: 10.7164/antibiotics.45.470.
3
New polyenic antibiotics active against gram-positive and gram-negative bacteria. VII. Isolation and structure of enacyloxin IVa, a possible biosynthetic intermediate of enacyloxin IIa.对革兰氏阳性菌和革兰氏阴性菌均有活性的新型多烯抗生素。VII. 恩西洛新IVa的分离与结构，它可能是恩西洛新IIa的生物合成中间体。
J Antibiot (Tokyo). 1992 Apr;45(4):575-6. doi: 10.7164/antibiotics.45.575.
4
New polyenic antibiotics active against gram-positive and gram-negative bacteria. V. Mode of action of enacyloxin IIa.
J Antibiot (Tokyo). 1991 Dec;44(12):1457-9. doi: 10.7164/antibiotics.44.1457.
5
Enacyloxin IIa, an inhibitor of protein biosynthesis that acts on elongation factor Tu and the ribosome.恩酰洛新IIa，一种作用于延伸因子Tu和核糖体的蛋白质生物合成抑制剂。
EMBO J. 1996 May 15;15(10):2604-11.
6
New polyenic antibiotics active against gram-positive and gram-negative bacteria. VIII. Construction of synthetic medium for production of mono-chloro-congeners of enacyloxins.
J Antibiot (Tokyo). 1992 Apr;45(4):476-84. doi: 10.7164/antibiotics.45.476.
7
Mutant EF-Tu species reveal novel features of the enacyloxin IIa inhibition mechanism on the ribosome.突变型EF-Tu物种揭示了恩酰毒素IIa在核糖体上抑制机制的新特征。
J Mol Biol. 1999 Dec 3;294(3):627-37. doi: 10.1006/jmbi.1999.3296.
8
Ribosome-catalyzed peptide-bond formation with an A-site substrate covalently linked to 23S ribosomal RNA.核糖体催化肽键形成，其中A位点底物与23S核糖体RNA共价连接。
Science. 1998 Apr 10;280(5361):286-9. doi: 10.1126/science.280.5361.286.
9
Lincosamide antibiotics stimulate dissociation of peptidyl-tRNA from ribosomes.林可酰胺类抗生素可刺激肽基 - tRNA从核糖体上解离。
Antimicrob Agents Chemother. 1993 Sep;37(9):2027-9. doi: 10.1128/AAC.37.9.2027.
10
GTP consumption of elongation factor Tu during translation of heteropolymeric mRNAs.异聚体mRNA翻译过程中延伸因子Tu的GTP消耗
Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):1945-9. doi: 10.1073/pnas.92.6.1945.
引用本文的文献
1
tRNAs as antibiotic targets.转运RNA作为抗生素靶点。
Int J Mol Sci. 2014 Dec 25;16(1):321-49. doi: 10.3390/ijms16010321.
Zotero 插件