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流式细胞术:概述。

Flow cytometry: an overview.

作者信息

Madeya M L, Pfab-Tokarsky J M

机构信息

Pittsburgh Cancer Institute, PA.

出版信息

Oncol Nurs Forum. 1992 Apr;19(3):459-63.

PMID:1375740
Abstract

Flow cytometry is a method of rapidly analyzing large numbers of cells as they flow in a liquid medium through a laser source. Flow cytometry provides valuable information regarding DNA content, RNA content, and the percentage of cells in the S phase of the cell cycle. This information can be used to predict the aggressiveness of many tumors, which has direct prognostic and diagnostic implications. Flow cytometry assists healthcare professionals in planning and implementing effective, appropriate, and timely interventions. Because flow cytometry is becoming more prevalent, nurses must be aware of its actual and potential applications. The data obtained from flow cytometry provide important information that can assist nurses in anticipating a particular regimen for specific tumors and in projecting the patient's clinical course. With this information, nurses can modify and individualize care plans. When used in conjunction with a patient's clinical presentation and other laboratory findings, flow cytometry has a direct impact on both treatment decisions and nursing interventions.

摘要

流式细胞术是一种在细胞于液体介质中流经激光源时,对大量细胞进行快速分析的方法。流式细胞术可提供有关DNA含量、RNA含量以及细胞周期S期细胞百分比的有价值信息。这些信息可用于预测许多肿瘤的侵袭性,具有直接的预后和诊断意义。流式细胞术有助于医护人员规划和实施有效、恰当且及时的干预措施。由于流式细胞术越来越普遍,护士必须了解其实际和潜在应用。从流式细胞术获得的数据提供了重要信息,可帮助护士为特定肿瘤预期特定治疗方案,并预测患者的临床病程。有了这些信息,护士可以修改并个性化护理计划。当与患者的临床表现及其他实验室检查结果结合使用时,流式细胞术对治疗决策和护理干预都有直接影响。

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