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不可逆失活后外周神经中乙酰胆碱酯酶的再生

Acetylcholinesterase regeneration in peripheral nerve after irreversible inactivation.

作者信息

KOENIG E, KOELLE G B

出版信息

Science. 1960 Oct 28;132(3435):1249-50. doi: 10.1126/science.132.3435.1249.

Abstract

The return of acetylcholinesterase activity was studied in several cholinergic structures in the cat after irreversible inactivation by diisopropylfluoro-phosphate. It was found that enzymic activity returned uniformly along the hypoglossal and cervical sympathetic nerve trunks. No evidence for somatoaxonal convection of enzyme was obtained.

摘要

在猫体内,通过二异丙基氟磷酸使其不可逆失活后,研究了几种胆碱能结构中乙酰胆碱酯酶活性的恢复情况。结果发现,酶活性沿舌下神经和颈交感神经干均匀恢复。未获得酶体轴突对流的证据。

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