KOENIG E, KOELLE G B
Science. 1960 Oct 28;132(3435):1249-50. doi: 10.1126/science.132.3435.1249.
The return of acetylcholinesterase activity was studied in several cholinergic structures in the cat after irreversible inactivation by diisopropylfluoro-phosphate. It was found that enzymic activity returned uniformly along the hypoglossal and cervical sympathetic nerve trunks. No evidence for somatoaxonal convection of enzyme was obtained.
在猫体内,通过二异丙基氟磷酸使其不可逆失活后,研究了几种胆碱能结构中乙酰胆碱酯酶活性的恢复情况。结果发现,酶活性沿舌下神经和颈交感神经干均匀恢复。未获得酶体轴突对流的证据。