猫和大鼠神经节乙酰胆碱酯酶与非特异性胆碱酯酶之间的相互关系。
Interrelationships between ganglionic acetylcholinesterase and nonspecific cholinesterase of the cat and rat.
作者信息
Koelle G B, Rickard K K, Ruch G A
出版信息
Proc Natl Acad Sci U S A. 1979 Nov;76(11):6012-6. doi: 10.1073/pnas.76.11.6012.
Abstract
When homogenates of cat or rat superior cervical ganglia in Krebs-Ringer solution were incubated at 37 degrees C, the ensuing decrease in acetylcholinesterase (acetylcholine acylhydrolase, EC 3.1.1.7) activity was increased significantly by prior administration in vivo of tetramonoisopropylpyrophosphotetramide at doses that produced selective alkylphosphorylation of butyrylcholinesterase or propionylcholinesterase. These findings are consistent with the proposal that the latter enzymes are posttranscriptional precursors of acetylcholinesterase. Results of similar studies with homogenates of ganglia in water or in M NaCl/1% Triton X-100 were inconclusive, as were those of heat-inactivation studies and immunoprecipitation of the enzymes.
摘要
当将猫或大鼠颈上神经节在 Krebs-Ringer 溶液中的匀浆在 37℃孵育时，体内预先给予能使丁酰胆碱酯酶或丙酰胆碱酯酶发生选择性烷基磷酸化的剂量的四单异丙基焦磷四酰胺，会使随后乙酰胆碱酯酶（乙酰胆碱酰基水解酶，EC 3.1.1.7）活性的降低显著增加。这些发现与后一种酶是乙酰胆碱酯酶转录后前体的提议一致。在水中或 0.15M NaCl/1% Triton X-100 中对神经节匀浆进行的类似研究结果尚无定论，热灭活研究和酶的免疫沉淀结果也是如此。
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本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
The histochemical identification of acetylcholinesterase in cholinergic, adrenergic and sensory neurons.胆碱能、肾上腺素能和感觉神经元中乙酰胆碱酯酶的组织化学鉴定。
J Pharmacol Exp Ther. 1955 Jun;114(2):167-84.
3
HISTONE REGULATION OF LACTIC DEHYDROGENASE IN EMBRYONIC CHICK BRAIN TISSUE.胚胎鸡脑组织中乳酸脱氢酶的组蛋白调控
Science. 1965 Apr 9;148(3667):242-4. doi: 10.1126/science.148.3667.242.
4
A new and rapid colorimetric determination of acetylcholinesterase activity.一种新的快速比色法测定乙酰胆碱酯酶活性。
Biochem Pharmacol. 1961 Jul;7:88-95. doi: 10.1016/0006-2952(61)90145-9.
5
Studies on cholinesterase. 9. Species variation in the specificity pattern of the pseudo cholinesterases.胆碱酯酶研究。9. 假性胆碱酯酶特异性模式的物种差异。
Biochem J. 1953 Aug;55(1):67-79. doi: 10.1042/bj0550067.
6
Further evidence for posttranscriptional control of inducible tyrosine aminotransferase synthesis in cultured hepatoma cells.培养的肝癌细胞中诱导型酪氨酸转氨酶合成的转录后调控的进一步证据。
Nat New Biol. 1972 Sep 6;239(88):9-14. doi: 10.1038/newbio239009a0.
7
Hormones and gene expression.
Annu Rev Genet. 1970;4:91-106. doi: 10.1146/annurev.ge.04.120170.000515.
8
Biochemical and histochemical observations on the postnatal development of cholinesterases in the sympathetic ganglion of the rat.大鼠交感神经节胆碱酯酶出生后发育的生化与组织化学观察
Histochem J. 1972 Nov;4(6):545-59. doi: 10.1007/BF01011133.
9
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Proc Natl Acad Sci U S A. 1976 Aug;73(8):2936-8. doi: 10.1073/pnas.73.8.2936.
10
The recovery of acetylcholinesterase activity in the superior cervical ganglion of the rat following its inhibition by diisopropylphosphorofluoridate: a biochemical and cytochemical study.大鼠颈上神经节中二异丙基氟磷酸酯抑制后乙酰胆碱酯酶活性的恢复：一项生化和细胞化学研究。
Neuroscience. 1976;1(5):413-21. doi: 10.1016/0306-4522(76)90134-2.
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