Fries R, Grabner H, Leijhanec J, Wepner F, Kränzl B, Krekeler G, Kriens O, Mehnert H, Platz H, Scharf F, Schroll K, Schulz P, Waldhart E, Zisser G, Schulz P, Schulz P
Zahn Mund Kieferheilkd Zentralbl. 1976;64(6):569-79.
Problems associated with the classification of cavum oris and labial carcinomata were discussed with particular reference to patients admitted to and treated in seven different clinical hospitals where identical methods of diagnosis and case history evaluation had been used. Using electronic data processing and biostatistical methods it was possible to study the effects of two clinically detectable factors (growth of primary tumor and degree of regional metastasizing) on both the prognosis and classification according to UICC rules. It was possible to show that a determination of the size of primary tumor (T) alone was not sufficient for three homogeneous, prognostically different collectives of tumors to be satisfactorily classified by the new UICC rules. It has been shown that a classification of three collectives of tumors (new classification according to UICC rules), especially as regards the proportion of N3 metastases within the collectives of tumors, was made possible. Therefore, it will be necessary to study the prognostic influences of additional clinically determinable factors with a view to arriving at a useful and practicable classification of oral cavity carcinomata.
讨论了口腔和唇癌分类相关的问题，特别参考了在七家不同临床医院收治和治疗的患者情况，这些医院采用了相同的诊断方法和病例史评估方法。利用电子数据处理和生物统计学方法，得以研究两个临床可检测因素（原发性肿瘤的生长和区域转移程度）对根据国际抗癌联盟（UICC）规则的预后和分类的影响。结果表明，仅确定原发性肿瘤的大小（T）不足以让新的UICC规则对三个同质、预后不同的肿瘤群体进行令人满意的分类。已经表明，可以对三个肿瘤群体进行分类（根据UICC规则的新分类），特别是关于肿瘤群体内N3转移的比例。因此，有必要研究其他临床可确定因素的预后影响，以期对口腔癌得出有用且可行的分类。
