胰岛素对完整原生动物中环鸟苷酸定位的快速作用。
Rapid effects of insulin on cyclic GMP location in an intact protozoan.
作者信息
Kohidai L, Barsony J, Roth J, Marx S J
机构信息
Metabolic Diseases Branch, NIDDK, Bethesda, Maryland 20892.
出版信息
Experientia. 1992 May 15;48(5):476-81. doi: 10.1007/BF01928167.
PMID:1376280
Abstract
We studied rapid changes in location of cyclic GMP in Tetrahymena pyriformis. Insulin caused cGMP localization in cilia and near the plasma membrane (0.5-1 min). Later (1-5 min) cGMP localization was diffuse in cytoplasm with perinuclear accentuation. Inactive insulin analogs did not elicit these changes.
摘要
我们研究了梨形四膜虫中环状鸟苷酸（cGMP）位置的快速变化。胰岛素导致cGMP定位于纤毛和质膜附近（0.5 - 1分钟）。之后（1 - 5分钟），cGMP在细胞质中呈弥漫性分布，并在核周更为明显。无活性的胰岛素类似物不会引发这些变化。
Zotero 插件