Lehmann A R, Hoeijmakers J H, van Zeeland A A, Backendorf C M, Bridges B A, Collins A, Fuchs R P, Margison G P, Montesano R, Moustacchi E
MRC Cell Mutation Unit, University of Sussex, Falmer, Brighton, Great Britain.
Mutat Res. 1992 Jan;273(1):1-28. doi: 10.1016/0921-8777(92)90046-6.
A workshop on DNA repair with emphasis on eukaryotic systems was held, under the auspices of the EC Concerted Action on DNA Repair and Cancer, at Noordwijkerhout (The Netherlands) 14-19 April 1991. The local organization of the meeting was done under the auspices of the Medical Genetic Centre South-West, The Netherlands (MGC), c/o Department of Radiation Genetics and Chemical Mutagenesis, University of Leiden (The Netherlands). Local organizers were: D. Bootsma (chairman), W. Ferro, J.H.J. Hoeijmakers, A.R. Lehmann, P.H.M. Lohman, L. Mullenders, and A.A. van Zeeland (secretarial assistance: Mrs. C. Escher-van Heerden and Mrs. R. Bontre). Over 190 scientists participated, and the format of the meeting followed that of the 1987 workshop on the 'Molecular Aspects of DNA Repair' (Friedberg et al., 1987). Plenary review talks in the mornings were followed, in the afternoon, by poster viewing in three or four parallel sessions. Groups of 15-20 posters were discussed in detail, and later on, in plenary sessions, chairpersons of the poster discussions reviewed the afternoons' posters. The principal themes of the meeting were the isolation and characterisation of repair genes and proteins, repair in specific sequences, consequences of defective DNA repair, and new methods for detecting DNA damage and repair. Remarkable progress has been made recently in all of these areas, and many exciting new results were presented. It is impossible to summarize all contributions to this (intensive) one-week meeting. Therefore, and for the sake of coherence, presentations that did not fit easily into any of the general themes of the meetings have not been included.
1991年4月14日至19日，在荷兰诺德韦克豪特，由欧洲共同体DNA修复与癌症协同行动主办，召开了一次以真核生物系统为重点的DNA修复研讨会。会议的当地组织工作由荷兰西南医学遗传中心（MGC）主持，地址为荷兰莱顿大学辐射遗传学与化学诱变系。当地组织者有：D. 博茨马（主席）、W. 费罗、J.H.J. 霍伊马克斯、A.R. 莱曼、P.H.M. 洛曼、L. 穆伦德斯以及A.A. 范泽兰（秘书协助：C. 埃舍尔 - 范海尔登夫人和R. 邦特雷夫人）。190多位科学家参加了会议，会议形式沿用了1987年“DNA修复的分子层面”研讨会的形式（弗里德伯格等人，1987年）。上午进行全体大会综述报告，下午则分三到四个平行场次进行海报展示。每场有15 - 20张海报进行详细讨论，之后在全体会议上，海报讨论的主持人对下午的海报进行综述。会议的主要主题包括修复基因和蛋白质的分离与特性、特定序列中的修复、DNA修复缺陷的后果以及检测DNA损伤和修复的新方法。最近在所有这些领域都取得了显著进展，会上展示了许多令人兴奋的新成果。要总结对这个为期一周的（紧凑）会议的所有贡献是不可能的。因此，为了连贯性，不符合会议任何一个总体主题的报告未被纳入。
