Farrell P C, Mahony J F, Jones B F, Mathew T H, Dawborn J K, Disney A P
Aust N Z J Med. 1976 Aug;6(4):292-7. doi: 10.1111/imj.1976.6.4.292.
A commercially available sorbent-based dialysate regeneration system has been compared to conventional single-pass dialysate delivery systems for treatment periods of six weeks in 13 patients on maintenance dialysis. The results of treatment were virtually identical in comparing sorbent and conventional systems except that seven of the eight patients using 2-5 M2 dialysers for 3--4 hours thrice per week developed asymptomatic metabolic acidosis with the dialysate regeneration system. This complication was not seen in the five patients using 1-3 M2 dialysers and having a 6--7 hour treatment thrice weekly. Dialysate regeneration systems are particularly suited for use when water supplies are limited or of insufficient purity for single-pass dialysis, and when a portable artificial kidney is required. To avoid metabolic acidosis with this system, using currently available disposable cartridges, each dialysis treatment should be of at least 4-5 hours duration.
一种市售的基于吸附剂的透析液再生系统已与传统的单通道透析液输送系统进行了比较，13名维持性透析患者接受了为期六周的治疗。比较吸附剂系统和传统系统的治疗结果几乎相同，只是在使用透析液再生系统的8名患者中，有7名每周三次使用2 - 5平方米透析器进行3 - 4小时治疗的患者出现了无症状代谢性酸中毒。在每周三次使用1 - 3平方米透析器进行6 - 7小时治疗的5名患者中未观察到这种并发症。当水源有限或纯度不足以进行单通道透析时，以及当需要便携式人工肾时，透析液再生系统特别适用。为避免使用该系统出现代谢性酸中毒，使用目前可用的一次性滤筒时，每次透析治疗应至少持续4 - 5小时。
