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通过可控去纤维蛋白原法改善实验性血管移植物通畅性

Improvement in experimental vascular graft patency by controlled defibrinogenation.

作者信息

Postlethwaite J C, Goyle K B, Dormandy J A, Hynd J W

出版信息

Br J Surg. 1977 Jan;64(1):28-30. doi: 10.1002/bjs.1800640107.

DOI:10.1002/bjs.1800640107
PMID:137762
Abstract

A sensitive animal model was used to investigate treatment designed to improve vascular graft patency. A Dacron graft was inserted into the infrarenal vena cava of 30 rabbits. Half were treated with subcutaneous Arvin for 28 days after operation. This produced a significant lowering of the post operative plasma fibrinogen. The patency rate of the grafts in the treated rabbits was significantly greater than in the control rabbits.

摘要

使用一种敏感的动物模型来研究旨在提高血管移植物通畅率的治疗方法。将涤纶移植物植入30只兔子的肾下腔静脉。其中一半在术后接受皮下注射阿文(Ancrod)治疗28天。这使得术后血浆纤维蛋白原显著降低。接受治疗的兔子的移植物通畅率明显高于对照兔子。

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