BANGHAM D R, MUSSETT M V
Bull World Health Organ. 1959;20(6):1201-8.
The Second International Standard for Heparin is a hygroscopic powder which was obtained by purifying and drying a batch of commercial beef heparin powder. In an international collaborative assay it was compared with the First International Standard, which it will now replace. As a result of the assay the seven participating laboratories agreed that the potencies of the two preparations did not differ significantly and the definition of the International Unit for Heparin remains unchanged as the activity contained in 0.0077 mg of the Second International Standard for Heparin.
《肝素第二国际标准品》是一种吸湿粉末，通过对一批商业牛肉肝素粉末进行纯化和干燥而获得。在一项国际协作测定中，它与现已被其取代的《肝素第一国际标准品》进行了比较。测定结果表明，七个参与实验室一致认为，这两种制剂的效价没有显著差异，肝素国际单位的定义保持不变，即0.0077毫克《肝素第二国际标准品》所含的活性。
