[The dynamics of latent inhibition in rats under the action of substance P].
作者信息
Loskutova L V, Skarina T I
出版信息
Zh Vyssh Nerv Deiat Im I P Pavlova. 1992 May-Jun;42(3):543-8.
PMID:1379770
Abstract
The role of substance P in latent inhibition was studied in experiments on rats. Administration of neuropeptide during pre-exposition of conditioned stimulus and before conditioning disturbed all signs of latent inhibition: level of reproduction, retention and resistance to amnestic action of conditioned reaction in the task of passive avoidance. Single administration of haloperidol before learning prevented the disturbance. Significance of hyperfunction of substance P in selective attention and pathogenesis of schizophrenia is discussed.
摘要
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