[Effect of aminazine and haloperidol on caudate inhibition of the conditioned reflex reaction of avoidance in cats].

The effect of neuroleptics on the avoidance behaviour under electric low-frequency stimulation of the caudate neucleus was studied in experiments with cats. Chlorpromazine (1 and 3 mg/kg) and haloperidol (0.5 mg/kg) were found to bring disorder in the behaviour of the animals and to intensify the inhibitory function of the caudate nucleus. Chlorpromazine proved in all respects to be a more active substance. The results obtained may be attributed to disruption of the central dopamine- and noradrenergic transmission.