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[纯化葡萄球菌产毒外毒素纠正抗原特异性和抗原非特异性免疫缺陷的能力]

[The capacity of purified staphylococcal anatoxin to correct antigen-specific and antigen-nonspecific immunological defects].

作者信息

Semenova I B, Vargin V V, Akatov A K

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1992 Apr(4):42-4.

PMID:1379773
Abstract

Purified staphylococcal toxoid is capable of partially preventing the development of antigen-specific (induced by the supraoptimal dose of sheep red blood cells) and antigen-nonspecific (induced by Tahyna virus) defects of humoral immune response, as well as abolishing these defects. The presence and manifestation of the correction of virus-induced immunodeficiency is determined by the dose of the toxoid and the interval between the injections of purified staphylococcal toxoid and the infective agent.

摘要

纯化的葡萄球菌类毒素能够部分预防体液免疫反应的抗原特异性缺陷(由超最佳剂量的绵羊红细胞诱导)和抗原非特异性缺陷(由塔希纳病毒诱导)的发生,还能消除这些缺陷。病毒诱导的免疫缺陷的纠正情况及其表现取决于类毒素的剂量以及纯化葡萄球菌类毒素注射与感染因子注射之间的间隔时间。

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