Marder S R
West Los Angeles Veterans Affairs Medical Center, Brentwood Division, CA.
Clin Neuropharmacol. 1992;15 Suppl 1 Pt A:92A-93A. doi: 10.1097/00002826-199201001-00049.
This multicenter trial indicates that risperidone is an effective treatment for the positive and negative symptoms of schizophrenia. The most effective dose appears to be about 6 mg of risperidone daily. This dose was more effective than 20 mg of haloperidol. In addition, this dose was associated with very low rates of extrapyramidal side effects.