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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Otsuka-Fuchino H, Watanabe Y, Hirakawa C, Tamiya T, Matsumoto J J, Tsuchiya T

Department of Chemistry, Faculty of Science and Technology, Sophia University, Tokyo, Japan.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1992 Apr;101(3):607-13. doi: 10.1016/0742-8413(92)90094-n.

Bactericidal action of a glycoprotein, Achacin, purified from the giant African snail, Achatina fulica Férussac, has been studied. 2. Achacin kills both gram-positive and gram-negative bacteria, but only in their growing states. 3. Achacin does not have any bacteriolytic activity. 4. The strain which has no cell wall is a little more sensitive than the native strain and the cell membrane-damaged strain. 5. Achacin was observed on the cytoplasmic membrane and on the cell wall of treated Escherichia coli by immunoelectron microscopy. 6. Achacin attacks the cytoplasmic membrane of the cell.

对从非洲大蜗牛（Achatina fulica Férussac）中纯化得到的一种糖蛋白——阿奇辛的杀菌作用进行了研究。2. 阿奇辛能杀死革兰氏阳性菌和革兰氏阴性菌，但仅在它们的生长状态下有效。3. 阿奇辛没有任何溶菌活性。4. 没有细胞壁的菌株比天然菌株和细胞膜受损的菌株稍敏感一些。5. 通过免疫电子显微镜观察到阿奇辛存在于经处理的大肠杆菌的细胞质膜和细胞壁上。6. 阿奇辛攻击细胞的细胞质膜。

Otsuka-Fuchino H, Watanabe Y, Hirakawa C, Tamiya T, Matsumoto J J, Tsuchiya T

Department of Chemistry, Faculty of Science and Technology, Sophia University, Tokyo, Japan.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1992 Apr;101(3):607-13. doi: 10.1016/0742-8413(92)90094-n.

Bactericidal action of a glycoprotein, Achacin, purified from the giant African snail, Achatina fulica Férussac, has been studied. 2. Achacin kills both gram-positive and gram-negative bacteria, but only in their growing states. 3. Achacin does not have any bacteriolytic activity. 4. The strain which has no cell wall is a little more sensitive than the native strain and the cell membrane-damaged strain. 5. Achacin was observed on the cytoplasmic membrane and on the cell wall of treated Escherichia coli by immunoelectron microscopy. 6. Achacin attacks the cytoplasmic membrane of the cell.

对从非洲大蜗牛（Achatina fulica Férussac）中纯化得到的一种糖蛋白——阿奇辛的杀菌作用进行了研究。2. 阿奇辛能杀死革兰氏阳性菌和革兰氏阴性菌，但仅在它们的生长状态下有效。3. 阿奇辛没有任何溶菌活性。4. 没有细胞壁的菌株比天然菌株和细胞膜受损的菌株稍敏感一些。5. 通过免疫电子显微镜观察到阿奇辛存在于经处理的大肠杆菌的细胞质膜和细胞壁上。6. 阿奇辛攻击细胞的细胞质膜。