Ersev D, Ilker Y, Simsek F, Kuyumcuoglu U, Akdas A
Kartal State Hospital, Urology Clinic, Istanbul, Turkey.
Eur Urol. 1992;21(3):187-91. doi: 10.1159/000474835.
This prospective study was conducted in order to evaluate the efficacy of transurethral microwave thermotherapy (TUMT) in the treatment of benign prostatic hyperplasia (BPH). A single TUMT session of 55 min was delivered as an ambulatory procedure without anesthesia to 180 patients. 20 (69%) of the 29 patients who were catheterized due to urinary retention prior to the treatment were able to urinate freely after the treatment. In 91 patients with a follow-up of 3 months, the mean maximum flow rate (MFR) was 7.9 ml/s prior to the treatment and 12.1 ml/s after the treatment (p less than 0.02). The mean residual urine after voiding (PVR) of these patients was 104 and 54 ml before and after TUMT, respectively (p = 0.0001). The mean Madsen symptom score (SS) was 14 before and 7.5 after the treatment (p = 0.0001). The patients with pretreatment MFR higher than 7.0 ml/s, PVR less than 150 ml and SS lower than 15 benefited better from TUMT. As the findings indicated, TUMT is an alternative treatment modality in BPH in selected cases, although the number and the follow-up of our series are insufficient to draw a precise conclusion yet.
本前瞻性研究旨在评估经尿道微波热疗(TUMT)治疗良性前列腺增生(BPH)的疗效。对180例患者进行了一次时长55分钟的门诊TUMT治疗,无需麻醉。29例在治疗前因尿潴留而留置导尿管的患者中,有20例(69%)在治疗后能够自主排尿。在91例随访3个月的患者中,治疗前平均最大尿流率(MFR)为7.9毫升/秒,治疗后为12.1毫升/秒(p<0.02)。这些患者排尿后平均残余尿量(PVR)在TUMT治疗前后分别为104毫升和54毫升(p=0.0001)。平均Madsen症状评分(SS)治疗前为14分,治疗后为7.5分(p=0.0001)。治疗前MFR高于7.0毫升/秒、PVR低于150毫升且SS低于15分的患者从TUMT中获益更大。研究结果表明,TUMT在某些特定病例的BPH治疗中是一种替代治疗方式,尽管本系列病例数量和随访时间不足以得出确切结论。