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子宫内膜腺癌中雌激素和孕激素受体的测定。刮宫活检中葡聚糖包被活性炭法与免疫酶法的比较。

Determination of estrogen and progesterone receptors in endometrial adenocarcinomas. Comparison between dextran-coated charcoal and immunoenzymatic methods on curettage biopsies.

作者信息

Marchal S, Marchal C, Hoffstetter S, Parache R M, Pernot M

机构信息

Centre Alexis Vautrin, Vandoeuvre les Nancy, France.

出版信息

Anticancer Res. 1992 Jul-Aug;12(4):1307-10.

PMID:1380228
Abstract

Estrogen receptors (ER) and progesterone receptors (PR) were determined on curettages from women with endometrial adenocarcinoma. The results obtained with the enzyme immunoassay (EIA) and the dextran-coated charcoal (DCC) assay were compared. A highly significant correlation was obtained between these methods for the ER measurement (Rs = 0.91). For PR determination, the Rs value between EIA and DCC assay was 0.57 and the mean value of PR-DCC is significantly higher than the mean value of PR-EIA. These results suggest that EIA is a suitable method for ER measurement. For PR determination on curettage material the DCC assay seems more accurate than EIA.

摘要

对子宫内膜腺癌女性的刮宫组织进行雌激素受体（ER）和孕激素受体（PR）检测。比较了酶免疫测定法（EIA）和葡聚糖包被活性炭（DCC）测定法的结果。两种方法在ER检测方面具有高度显著的相关性（Rs = 0.91）。对于PR测定，EIA和DCC测定法之间的Rs值为0.57，且PR-DCC的平均值显著高于PR-EIA的平均值。这些结果表明，EIA是检测ER的合适方法。对于刮宫材料的PR测定，DCC测定法似乎比EIA更准确。

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