Kramer M R, Berkman N, Weshler Z
Pulmonary Institute, Hadassah-Hebrew University Medical Center, Ein Karem, Jerusalem.
Harefuah. 1992 Jun 15;122(12):760-3, 820.
Intrabronchial obstruction is one of the serious complications of primary and secondary lung tumors. Brachytherapy (intraluminal irradiation) aims at palliation and opening airway obstruction. Of our first 10 patients, 4 had primary and 6 metastatic pulmonary lesions. Brachytherapy was administered through the fiberoptic bronchoscope under topical anesthesia from a 192iridium source delivered with an afterload system. In 3 patients laser therapy was used initially. In 6 complete opening of the airway was achieved, and in 3 others partial opening. In all patients there was symptomatic relief without significant side-effects. We conclude that endobronchial brachytherapy is a safe, useful procedure for palliation of malignant endobronchial obstruction.
支气管内阻塞是原发性和继发性肺部肿瘤的严重并发症之一。近距离放射治疗(腔内照射)旨在缓解症状并解除气道阻塞。在我们最初的10例患者中,4例为原发性肺部病变,6例为转移性肺部病变。近距离放射治疗是在局部麻醉下通过纤维支气管镜,使用后装系统从铱-192源进行的。3例患者最初使用了激光治疗。6例患者气道完全开通,另外3例部分开通。所有患者症状均得到缓解,且无明显副作用。我们得出结论,支气管内近距离放射治疗是缓解恶性支气管内阻塞的一种安全、有效的方法。