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[近距离放射治疗:原发性和继发性支气管肿瘤的支气管内照射]

[Brachytherapy: endobronchial irradiation for primary and secondary bronchial tumors].

作者信息

Kramer M R, Berkman N, Weshler Z

机构信息

Pulmonary Institute, Hadassah-Hebrew University Medical Center, Ein Karem, Jerusalem.

出版信息

Harefuah. 1992 Jun 15;122(12):760-3, 820.

PMID:1380474
Abstract

Intrabronchial obstruction is one of the serious complications of primary and secondary lung tumors. Brachytherapy (intraluminal irradiation) aims at palliation and opening airway obstruction. Of our first 10 patients, 4 had primary and 6 metastatic pulmonary lesions. Brachytherapy was administered through the fiberoptic bronchoscope under topical anesthesia from a 192iridium source delivered with an afterload system. In 3 patients laser therapy was used initially. In 6 complete opening of the airway was achieved, and in 3 others partial opening. In all patients there was symptomatic relief without significant side-effects. We conclude that endobronchial brachytherapy is a safe, useful procedure for palliation of malignant endobronchial obstruction.

摘要

支气管内阻塞是原发性和继发性肺部肿瘤的严重并发症之一。近距离放射治疗(腔内照射)旨在缓解症状并解除气道阻塞。在我们最初的10例患者中,4例为原发性肺部病变,6例为转移性肺部病变。近距离放射治疗是在局部麻醉下通过纤维支气管镜,使用后装系统从铱-192源进行的。3例患者最初使用了激光治疗。6例患者气道完全开通,另外3例部分开通。所有患者症状均得到缓解,且无明显副作用。我们得出结论,支气管内近距离放射治疗是缓解恶性支气管内阻塞的一种安全、有效的方法。

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