Aradachi H, Yamashima T, Tuchida A, Noguchi Y, Kubota T
Department of Neurosurgery, Sabae Kimura Hospital.
No Shinkei Geka. 1992 Aug;20(8):883-6.
Verbal recent memory disturbance was observed in a patient with a malignant glioma associated with left hippocampal atrophy. A 25 year-old male was admitted because of seizures. CT scan and MRI showed enhanced mass lesions in the left temporal lobe associated with ipsilateral hippocampal atrophy. Neurological examination disclosed right homonymous hemianopsia, word amnesia, alexia, agraphia and acalculia. Neuropsychological examination disclosed verbal recent memory disturbance, which consisted of impaired recall of the precisely memorized words after some interruption. Although hippocampal lesions are known to be often associated with cerebrovascular disease, hippocampal atrophy due to brain tumor is quite unusual. This case suggested that the left hippocampus is closely related to verbal recent memory. Hippocampal atrophy in this case conceivably derived from the decreased arterial flow due to perifocal edema or obstructive hydrocephalus.
在一名患有与左侧海马萎缩相关的恶性胶质瘤患者中观察到言语近期记忆障碍。一名25岁男性因癫痫发作入院。CT扫描和MRI显示左侧颞叶有强化肿块病变，伴有同侧海马萎缩。神经学检查发现右侧同向性偏盲、单词遗忘、失读、失写和失算。神经心理学检查发现言语近期记忆障碍，表现为在经过一段时间中断后，对精确记忆单词的回忆受损。虽然已知海马病变常与脑血管疾病有关，但脑肿瘤导致的海马萎缩相当罕见。该病例表明左侧海马与言语近期记忆密切相关。该病例中的海马萎缩可能源于病灶周围水肿或梗阻性脑积水导致的动脉血流减少。
