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Down's syndrome: karyotypic stability of trisomy 21 in an established lympho-blastoid cell line.

作者信息

Miyoshi I, Masuji H, Fujiwara S, Kubonishi I, Kishimoto H

出版信息

Acta Med Okayama. 1976 Dec;30(6):403-6.

PMID:138335
Abstract

A trisomic lymphoblastoid cell line derived from the peripheral blood of a patient with Down's syndrome was sequentially analyzed for chromosome constitution for 16.5 months of continuous culture in vitro. The cell line was found to maintain a modal chromosome number of 47 with trisomy 21. Parallel studies of modal chromosomes before and after banding procedures revealed no structural abnormalities except trisomy 21.

摘要

相似文献

1
Down's syndrome: karyotypic stability of trisomy 21 in an established lympho-blastoid cell line.
Acta Med Okayama. 1976 Dec;30(6):403-6.
2
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