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[脑脉通对犬脑血流量的影响]

[Influences of naomaitong upon cerebral blood flow in dogs].

作者信息

He G, Chen X, Chang L, Liu J, Ye S, Yang J

机构信息

Institute of Chinese Materia Medica, Hubei College of Traditional Chinese Medicine, Wuhan.

出版信息

Zhongguo Zhong Yao Za Zhi. 1992 Mar;17(3):178-80, inside backcover.

PMID:1384544
Abstract

This experiment has proven that the drug naomaitong can synchronously increase the blood flow of both dog's internal carotid artery and vertebral artery and also can antagonize the decrease of blood flow of both arteries caused by pituitrin. The increase of blood flow of both internal carotid artery and vertebral artery due to administration of naomaitong (1.2 g/kg) through the dog's duodenum is approximately equal to the increase of blood flow of both arteries resulting from the intramuscular injection of papaverine (1 mg/kg). Besides, the dosage of naomaitong is positively correlated to the effect and action of the drug.

摘要

本实验证明,药物脑脉通能同步增加犬颈内动脉和椎动脉的血流量,还能拮抗垂体后叶素所致的这两条动脉血流量的减少。经犬十二指肠给予脑脉通(1.2g/kg)后,颈内动脉和椎动脉血流量的增加量约等于肌肉注射罂粟碱(1mg/kg)后这两条动脉血流量的增加量。此外,脑脉通的剂量与药物的效果和作用呈正相关。

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