Dodds-Smith M E, Johnson M S, Thompson D J
Department of Environmental and Evolutionary Biology, University of Liverpool, United Kingdom.
Ecotoxicol Environ Saf. 1992 Aug;24(1):118-30. doi: 10.1016/0147-6513(92)90040-a.
The distributions of trace metals in tissues of shrews in a series of feeding trials are described. The relationship between body cadmium burden and organ weight was directly related to differences in body weight. Organ weight expressed as a percentage of body weight was constant in the kidney, but was correlated with cadmium burden for the liver. Liver and kidney accounted for up to 80% of total body cadmium. The proportion of the body cadmium burden found in the kidney ranged from 8 to 17%. Copper and zinc concentrations in the kidney increased in response to cadmium accumulation. Hepatic zinc concentrations increased with cadmium accumulation. Exposure to a copper-contaminated diet resulted in increased liver copper levels. High liver concentrations were correlated with high kidney concentrations. At the lowest levels of exposure to metals liver and kidney concentrations were similar, but as exposure increased so did liver concentrations and much more so than in the kidney.
描述了一系列喂养试验中鼩鼱组织中痕量金属的分布情况。体内镉负荷与器官重量之间的关系与体重差异直接相关。以体重百分比表示的器官重量在肾脏中是恒定的，但与肝脏中的镉负荷相关。肝脏和肾脏中的镉含量占全身镉总量的比例高达80%。肾脏中镉负荷占全身的比例在8%至17%之间。随着镉的积累，肾脏中的铜和锌浓度升高。肝脏中的锌浓度随着镉的积累而增加。接触受铜污染的饮食会导致肝脏铜含量增加。肝脏中高浓度的铜与肾脏中高浓度的铜相关。在最低金属暴露水平下，肝脏和肾脏中的浓度相似，但随着暴露量增加，肝脏中的浓度增加，且增加幅度远大于肾脏。
