Fulton J E, Bradley S, Aqundez A, Black T
Cutis. 1976 Feb;17(2):344-5, 349-51.
The need for a "comedogenic-free" cosmetic for acne patients led to this study using the only available mode, the rabbit. To facilitate the formulation of this benign cover-up, a range of cosmetics and ingredients was tested. Many cosmetics, fractions, and modifications of lanolins were comedogenic, as were emulsifiers such as butyl sterate, isopropyl myristate and sodium lauryl sulfate. From this data we incorporated non-comedogenic, into an acceptable cosmetic formulation for patients. The use of this formulation in susceptible acne-prone women reduced the rate of "acne cosmetica" in our clinic patients from 25% to less than 5%. We were unable to confirm a recent study suggesting that sulfur was a potent acnegen.
痤疮患者对“无致粉刺性”化妆品的需求促使开展了这项以兔子为唯一可用实验对象的研究。为了便于调配这种温和的遮瑕产品，对一系列化妆品及成分进行了测试。许多化妆品、羊毛脂馏分及其改性产品都有致粉刺性，丁基硬脂酸酯、肉豆蔻酸异丙酯和月桂醇硫酸酯钠等乳化剂也是如此。根据这些数据，我们将无致粉刺性成分融入了一种适合患者使用的化妆品配方中。在易患痤疮的敏感女性中使用该配方后，我们诊所患者的“化妆品性痤疮”发病率从25%降至5%以下。我们无法证实最近一项表明硫是一种强效致痤疮物的研究。
