Brunel P
Pharma recherche et développement, Ciba-Geigy Ltd, Bâle, Suisse.
Arch Mal Coeur Vaiss. 1992 Apr;85(4):417-22.
The aim of this study was to assess the intra-observer reproducibility at short and medium term of three non-invasive methods of arterial measurement: in the same day eight volunteers underwent five successive measurements of brachial artery diameter by two dimensional pulsed Doppler of the carotido-femoral pulse wave velocity by a piezoelectric transducer. The measurements were repeated three times at two weeks' interval. The short term (same day) and medium term (after several weeks) reproducibility of the first two methods of measurement was good: 4.69 +/- 2.37%/4.24 +/- 1.90% and 4.09 +/- 1.16%/5.02 +/- 1.71% respectively for brachial artery diameter and carotido-femoral pulse wave velocity. The reproducibility of the method of measuring digital pulse wave velocity was 10.64 +/- 3.50%/11.62 +/- 4.25%, confirming the greater variability of this parameter. Our results with these noninvasive techniques indicate that they may be used to study the arterial system and could be clinically useful in the surveillance of hypertensive patients.
同一天,八名志愿者通过二维脉冲多普勒对肱动脉直径进行了五次连续测量,并通过压电换能器对颈股脉搏波速度进行了测量。测量每隔两周重复三次。前两种测量方法在短期(同一天)和中期(几周后)的重复性良好:肱动脉直径和颈股脉搏波速度的重复性分别为4.69±2.37%/4.24±1.90%和4.09±1.16%/5.02±1.71%。测量数字脉搏波速度方法的重复性为10.64±3.50%/11.62±4.25%,证实了该参数的变异性更大。我们使用这些无创技术的结果表明,它们可用于研究动脉系统,并且在高血压患者的监测中可能具有临床应用价值。