Ueda I, Tagawa T, Watanabe S, Yamakawa K, Yasu T, Ueda S
Department of Clinical Pharmacology and Therapeutics, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
J Hum Hypertens. 2008 Oct;22(10):699-703. doi: 10.1038/jhh.2008.57.
To evaluate the comparability and reproducibility of the carotid-femoral pulse wave velocity (PWV) measured by the newly developed device compared to that measured by the standard device and the validity of brachial-ankle PWV as a substitute of carotid-femoral PWV. We measured aortic PWV twice in 21 normotensive males by using the standard devices and the newly developed device. We also measured brachial-ankle PWV in the same subjects. There was a strong, significant correlation between aortic (carotid-femoral) PWV measured by using two different devices (r = 0.741, P = 0.00012). Interquartile range of the differences of carotid-femoral PWV measured by Form (0.75 m/s (-0.36, 0.39)) was smaller than that by Complior (1.67 m/s (-1.03, 0.63)). There was no correlation between carotid-femoral PWV, measured by either device, and brachial ankle PWV. Our present results suggest that carotid-femoral PWV measured by using Form was comparable to, and may be more reproducible than, that measured by Complior that has been widely used as a predictable marker for cardiovascular events. Our results also suggest brachial-ankle PWV may not be a substitute for carotid-femoral PWV.
为了评估新开发的设备所测量的颈股脉搏波速度（PWV）与标准设备所测量的PWV的可比性和可重复性，以及肱踝PWV替代颈股PWV的有效性。我们使用标准设备和新开发的设备，对21名血压正常的男性进行了两次主动脉PWV测量。我们还测量了同一受试者的肱踝PWV。使用两种不同设备测量的主动脉（颈股）PWV之间存在强烈且显著的相关性（r = 0.741，P = 0.00012）。Form测量的颈股PWV差异的四分位间距（0.75 m/s（-0.36，0.39））小于Complior测量的（1.67 m/s（-1.03，0.63））。两种设备测量的颈股PWV与肱踝PWV之间均无相关性。我们目前的结果表明，使用Form测量的颈股PWV与Complior测量的具有可比性，并且可能比Complior测量的更具可重复性，Complior已被广泛用作心血管事件的预测指标。我们的结果还表明，肱踝PWV可能无法替代颈股PWV。
