Kaelin L D, Klingman N, Normann S J, Seeger J M
Department of Surgery, University of Florida, Gainesville 32610-0286.
Lasers Surg Med. 1992;12(4):410-6. doi: 10.1002/lsm.1900120410.
Polytetrafluoroethylene (PTFE) and Dacron grafts were implanted in canine femoral and carotid arteries using PTFE and Prolene suture, respectively. Arteries containing occluded grafts were explanted and laser recanalization was attempted in vitro. Laser recanalization was successful in 78% of PTFE grafts compared to 30% of Dacron grafts. Recanalization was complete (residual stenosis less than 5%) in opened PTFE grafts, whereas residual stenosis averaged 60% in recanalized Dacron grafts. PTFE graft/PTFE suture anastomotic tensile strength was unchanged after recanalization, while Dacron graft/Prolene suture anastomotic tensile strength decreased significantly. In addition, anastomotic bursting pressure was significantly higher for lased PTFE grafts with PTFE sutures (300 mg Hg) compared to lased Dacron grafts with Prolene sutures (70 mm Hg). Chronically occluded PTFE grafts with PTFE suture can be safely and effectively opened by laser recanalization. In contrast, attempted laser recanalization of Dacron grafts sutured with Prolene suture is seldom successful, significantly weakens the graft artery anastomosis, and should be avoided.
分别使用聚四氟乙烯（PTFE）和普理灵缝线将聚四氟乙烯（PTFE）和涤纶移植物植入犬的股动脉和颈动脉。取出含有闭塞移植物的动脉，并尝试在体外进行激光再通术。PTFE移植物的激光再通成功率为78%，而涤纶移植物为30%。再通后的开放PTFE移植物再通完全（残余狭窄小于5%），而再通后的涤纶移植物残余狭窄平均为60%。再通后PTFE移植物/PTFE缝线吻合口抗张强度不变，而涤纶移植物/普理灵缝线吻合口抗张强度显著降低。此外，与用普理灵缝线的激光再通涤纶移植物（70 mmHg）相比，用PTFE缝线的激光再通PTFE移植物的吻合口破裂压显著更高（300 mmHg）。用PTFE缝线的慢性闭塞PTFE移植物可通过激光再通术安全有效地开通。相比之下，尝试用普理灵缝线缝合的涤纶移植物进行激光再通很少成功，会显著削弱移植物与动脉的吻合，应避免使用。
